Open AccessCorrection of the oxidation stress by trimetazidine in blood of patients with after myocardial infarction cardiosclerosis
Author(s) -
И. Л. Давыдкин,
В. Н. Фатенков
Publication year - 2001
Publication title -
kazanskij medicinskij žurnal
Language(s) - English
Resource type - Journals
eISSN - 2587-9359
pISSN - 0368-4814
DOI - 10.17816/kazmj84062
Subject(s) - trimetazidine , cardiology , myocardial infarction , medicine , angina , stable angina , infarction , oxidative stress
The results of studies of the possibilities and mechanisms of correcting the oxidation stress in patients with cardiosclerosis after myocardial infarction, correlating with stable stress stenocardia of the 111 functional class are given. The treatment by trimetazidin of 34 patients in the daily dose of 60 mg within two months is carried out. Trimetazidine treatment in patients with angina after myocardial infarction decreases indices of metabolic oxidative stress. Trimetazidine treatment is accompanied by decrease in incidence and severity of angina and increase of physical tolerance.