Open AccessPlasmapheresis and hyperbaric oxygenation in the treatment of psoriasis complicated by polyarthritis
Author(s) -
V. N. Korobkov,
G. G. Slepukha,
I. G. Yapparov,
А. K. Saetgaraev
Publication year - 2001
Publication title -
kazanskij medicinskij žurnal
Language(s) - English
Resource type - Journals
eISSN - 2587-9359
pISSN - 0368-4814
DOI - 10.17816/kazmj83870
Subject(s) - psoriasis , inflammation , immune system , polyarthritis , medicine , immunology , plasmapheresis , disease , edema , immunity , antibody , arthritis , pathology
Treatment of psoriasis (Ps) is still one of the most difficult tasks of practical medicine. The disease often affects young and able-bodied people, and the process itself has a persistent and progressive nature, not amenable to treatment by traditional methods. PS as a systemic disease is based on the phenomena of chronic nonspecific skin inflammation with intracellular edema, infiltration, microcirculatory and metabolic disorders. PS is also characterized by disorders of oxidative processes in skin cells and in the system of free-radical oxidation of lipids. The study of immune status in PS patients revealed disorders of circulating immune complexes (CIC), in particular immunoglobulins A, M, G, against the background of suppressed cellular immunity and phagocytic activity of neutrophils.