Open AccessEfficiency of using calcium antagonists in the treatment of hypoxic intracranial hemorrhages in newborns
Author(s) -
Е. В. Левитина,
Г. А. Иваничев
Publication year - 2001
Publication title -
kazanskij medicinskij žurnal
Language(s) - English
Resource type - Journals
eISSN - 2587-9359
pISSN - 0368-4814
DOI - 10.17816/kazmj83866
Subject(s) - nimodipine , calcium , medicine , hypoxia (environmental) , calcium in biology , anesthesia , chemistry , oxygen , organic chemistry
The prospective observation and clinico-biochemical examination of 55 infants with intracranial hemorrhages from the neonatal period till one year old are carried out. The interrelation of disturbances of enzyme activity of electrolyte transmembrane transport and calcium level in thrombocytes with the character, gravity degree, clinical syndromes and course of the pathological process is revealed. The decrease of Ca2+-AT phase activity and the increase of intracellular calcium level in patients with the chronic and combined character of hypoxia are noted. The clinical and biochemical efficiency of calcium antagonists (nimodipine) in children with perinatal intracranial hemorrhages is determined.