
Concentration of antimicrobic antibodies in children with diabetes mellitus of the 1st type
Author(s) -
I. M. Filimonova,
Л. М. Султанова
Publication year - 2001
Publication title -
kazanskij medicinskij žurnal
Language(s) - English
Resource type - Journals
eISSN - 2587-9359
pISSN - 0368-4814
DOI - 10.17816/kazmj83859
Subject(s) - antibody , glycolipid , humoral immunity , diabetes mellitus , type 2 diabetes mellitus , immunity , immunology , medicine , chemistry , endocrinology , immune system
The state of antibacterial humoral immunity in 121 children with diabetes mellitus of the 1st type is shown using the hard phase immunoenzymic analysis. The increase of the level of antibodies to glycolipid independent of the degree of carbohydrate metabolism is revealed. The analysis of concentration of E. coli antibodies showed the changes similar to antibodies to glycolipid. Increas in the levels of glycolipid and E. coli antibodies in children with diabetes mellitus of the 1st type is justified by the excess supply of endotoxin from the enteric tract and is the result of its immunogenic properties.