The use of nibufin for fractures of tubular bones | Zendy

U. Ya. Bogdanovich | Zendy; F. Sh. Bakhtiozin | Zendy; В. П. Прохоров | Zendy

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The use of nibufin for fractures of tubular bones

Author(s) -

U. Ya. Bogdanovich,

F. Sh. Bakhtiozin,

В. П. Прохоров

Publication year - 1969

Publication title -

kazan medical journal

Language(s) - English

Resource type - Journals

eISSN - 2587-9359

pISSN - 0368-4814

DOI - 10.17816/kazmj79836

Subject(s) - smooth muscle , peristalsis , chemistry , uterus , pharmacology , anatomy , biophysics , medicine , biochemistry , biology

Nibufin, a paranitrophenyl ester of dibutylphosphinic acid, was synthesized at the Laboratory of Organic Chemistry. A.E. Arbuzov KHTI A.I. Razumov and O.A.Mukhacheva (1957). The drug was pharmacologically examined and proposed for practical use by IV Zaikonnikova (1961). As her studies have shown, nibufin has a pronounced anticholinesterase property, increases the tone of smooth muscle organs - the intestines, uterus, and enhances peristalsis. Compared with other organophosphorus compounds used in medicine - armin, phosphacol, phosarbin, it is much less toxic.

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