
Endotracheal administration of epinephrine for the treatment of pulmonary hemorrhage
Publication year - 1929
Publication title -
kazanskij medicinskij žurnal
Language(s) - English
Resource type - Journals
eISSN - 2587-9359
pISSN - 0368-4814
DOI - 10.17816/kazmj78922
Subject(s) - medicine , epinephrine , pulmonary hemorrhage , anesthesia , pulmonary arterial pressure , vasoconstriction , blood pressure , lung , hemodynamics
For stopping pulmonary hemorrhages tbc character Giuffrida. (Mnch M. Woch. 1928, No. 7) recommends the introduction of adrenaline into the cavity of the tracheobronchial tree above the vocal cords in the amount of one mlgr. (in 3 cubic meters, cmt of water). Out of 50 cases, in 45 the author was able to stop pulmonary hemorrhage, and in 12 cases one injection was sufficient. The duration of action of adrenaline is limited to 12 hours, after which the bleeding often resumes. The author recommends doing injections for 4 days, and for the first time two days, two injections a day, then one at a time. The mechanism of action of adrenaline is not to increase blood pressure, but to local vasoconstriction.