Clinical standardization of tuberculin drugs

The biological activity of tbc processes is best revealed by using intra-skin tests. Model and Sinelnikova (Vopr. Tub., 1928, No. 7-8), on the basis of their observations, come to the conclusion that ATK Nshst'a is the most suitable for this purpose. Comparing ATK preparations produced by the Central Bacteriological Institute (Moscow) and the 1st Ukrainian San. Bact. Institute (Kharkov), the authors consider them close to the drug Hchst'a. Albumosefrei Hchst is close to ATK Hchst'a and has some advantages over the latter. It does not contain foreign impurities (albumosis and peptones) that distort the biological effect of tuberculin, which is why the authors recommend the distribution of this drug for diagnostic and therapeutic purposes. Denys, Rosenbach'a and Kresling'a preparations are reduced in comparison with Hchst'a ATK. while Tuberculol, i.e. the aqueous extract of VC, is very close to ATK.