Rheumatism

The author injected under the skin of healthy rabbits sterile extracts of a number of substances (cow, calf, pig and chicken meat, milk, eggs, etc.). After 3-4 weeks of repeated injections (once every 8-10 days), the same extract was injected near or into the joint. Within 24 hours, the joint was swollen and a local and general reaction similar to that observed in acute rheumatism was obtained.