Open AccessHypertrophic cardiomyopathy
Author(s) -
А. S. Galyavich,
В. Н. Ослопов,
Z. Sh. Khasanov,
A. I. Nefyodova,
E. N. Zagainova
Publication year - 1989
Publication title -
kazanskij medicinskij žurnal
Language(s) - English
Resource type - Journals
eISSN - 2587-9359
pISSN - 0368-4814
DOI - 10.17816/kazmj100649
Subject(s) - hypertrophic cardiomyopathy , penetrance , ventricle , cardiology , medicine , heredity , interventricular septum , concentric hypertrophy , etiology , cardiomyopathy , muscle hypertrophy , myocardial hypertrophy , disease , left ventricular hypertrophy , biology , heart failure , genetics , phenotype , blood pressure , gene
Hypertrophic cardiomyopathy is due to a so-called primary myocardial lesion. In typical cases, the interventricular septum is hypertrophied to a greater extent than the free wall of the left ventricle. Another variation of this disease is uniform concentric myocardial hypertrophy with a significant increase in heart mass. Although the etiology of hypertrophic cardiomyopathy is unknown, it is thought to be genetically determined by autosomal dominant transmission with a high degree of penetrance. The burdened heredity and familial nature of the disease occur in almost 60% of these patients, so the examination of their close relatives is of particular interest.