Open AccessParticularities of morphogenesis of human fetus brain
Author(s) -
Olga E. Talantova
Publication year - 2002
Publication title -
žurnalʺ akušerstva i ženskihʺ boleznej
Language(s) - English
Resource type - Journals
eISSN - 1684-0461
pISSN - 1683-9366
DOI - 10.17816/jowd90422
Subject(s) - morphogenesis , neuroscience , histogenesis , human brain , medicine , brain development , fetus , pathology , biology , pregnancy , immunohistochemistry , genetics , gene
The review is devoted to the basic events of human fetal CNS development. The cellular processes of two broad phases of cerebral morphogenesis cytogenesis/histogenesis and differentiation/growth are described. In this review we also concern the main regressive events in the CNS development such as programmed cell death (apoptosis), axonal pruning and synaptic elimination. Different environmental factors may effect human brain development even from its early stages causing brain injury that can result in major or minor cerebral malformations. So, the knowledge of the main questions of fetal brain morphogenesis can helpto prevent some abnomalities of CNS in the future child development.