
Common loss of the I-th three months gestation, observation tactics
Author(s) -
V. M. Sidelnicova,
V. V. Sosnina
Publication year - 2002
Publication title -
žurnalʺ akušerstva i ženskihʺ boleznej
Language(s) - English
Resource type - Journals
eISSN - 1684-0461
pISSN - 1683-9366
DOI - 10.17816/jowd90374
Subject(s) - gestation , medicine , pregnancy , placenta , fetus , trophoblast , early pregnancy loss , etiology , obstetrics , gynecology , complication , endometritis , placental insufficiency , biology , genetics
The common loss of gestation is a poly etiological complication during pregnancy time, where together with causes and factors of embryo/fetus peril there are destructions of the conjugal reproductive system. Main disturbances due to aborts in early terms are cariotype breakages: chromosome translocations and inversions were revealed in 8, 8% of inspected conjugal pairs, cariotype peculiarities in 72, 7%, conjugal compatibility according to HL А тогеЗ antigens was detected in 59, 3%. Disturbances of trophoblast invasion processes and placenta formation are evident because of hormonal distortions (NLF, hyperandrogeny), autoimmune distortions and chronicle endometritis with high level of anti-inflammatory cytokines. The development of placenta insufficiency in patients with these disturbances leads to pregnancy interruption.