Open AccessPplication estrogens and gestogens at autoimmune ovaritis
Author(s) -
К. А. Габелова,
А. М. Гзгзян,
М. Н. Богданова,
В. В. Потин,
Platon P. Khokhlov
Publication year - 2003
Publication title -
žurnalʺ akušerstva i ženskihʺ boleznej
Language(s) - English
Resource type - Journals
eISSN - 1684-0461
pISSN - 1683-9366
DOI - 10.17816/jowd88799
Subject(s) - ovary , medicine , amenorrhea , endocrinology , estrogen , menstruation , hormone , menstrual cycle , prolactin , physiology , pregnancy , biology , genetics
One studied hormonal indices (FSG, LG, prolactin, estradiol, progesterone) and anti-ovary auto anti-body contents in blood of 39% patients of reproductive age with autoimmune ovaritis. It was revealed in 18 patients the hypergonadotrope ovary insufficiency, which manifested itself as amenorrhea, in 21 patients the normogonsdotrope ovary insufficiency, which manifested itself as opsooligoamenorrhea or amenorrhea. Number of anti-ovary auto anti-bodies in blood was significantly more in studied patients than in healthy women. The statistically reliable decrease of anti-ovary auto anti-bodies happened in most patients in 6 months of estrogen and gestagen therapy. Restoration of ovary menstrual cycle happened in part of patients with normogonadotrope form of autoimmune ovaritis after such a therapy repeal. Authors associate therapeutic effect with decreasing gonadotrope ovary stimulation and with influence of estrogens and gestagens upon the immune system.