Open AccessProgesterone-related changes in pro-inflammatory cytokines in recurrent miscarriage
Author(s) -
V.E. Radzinsky,
E. Y. Zapertova
Publication year - 2004
Publication title -
žurnalʺ akušerstva i ženskihʺ boleznej
Language(s) - English
Resource type - Journals
eISSN - 1684-0461
pISSN - 1683-9366
DOI - 10.17816/jowd88652
Subject(s) - medicine , miscarriage , abortion , obstetrics , pregnancy , recurrent miscarriage , christian ministry , first trimester , gynecology , obstetrics and gynaecology , russian federation , fetus , philosophy , genetics , theology , business , biology , economic policy
Habitual miscarriage (RMP) is a multifactorial, genetically determined disease. The NSP problem remains one of the most pressing problems in obstetrics and gynecology, as it entails not only a decrease in the birth rate, but also has a negative impact on the reproductive health of women. The frequency of spontaneous miscarriages ranges from 15 to 20% of desired pregnancies (Sidelnikova V.M., 2002). According to the Collegium of the Ministry of Health of the Russian Federation (2002), 50% of miscarriages occur in the first trimester, 25% of them occur in PNL. Moreover, every fifth desired pregnancy is interrupted spontaneously in the Russian Federation, which leads not only to medical but also demographic losses - 180,000 desired children are not born in the country. In the USA, habitual pregnancy loss (recurrent miscarriage) is diagnosed after three or more spontaneous abortions in a row and is observed in 1% of all married couples (Lee R.M., 2000).