Open AccessPositive experience of replacement hormonal therapy in patients with climacteric syndrome with Proginova, Cyclo-Proginova and Climen
Author(s) -
A. S. Vishnevsky,
N. R. Safronnikova,
N. U. Melnikova,
T. N. VIadykina,
Е. А. Артамонова
Publication year - 1999
Publication title -
žurnalʺ akušerstva i ženskihʺ boleznej
Language(s) - English
Resource type - Journals
eISSN - 1684-0461
pISSN - 1683-9366
DOI - 10.17816/jowd87977
Subject(s) - climacteric , hormonal replacement therapy , medicine , hormone , hormone replacement therapy (female to male) , menopause , normalization (sociology) , physiology , hormonal therapy , postmenopausal women , gynecology , gastroenterology , endocrinology , testosterone (patch) , sociology , anthropology , prostate cancer , cancer
At 75 patients (average age 57,2 years, average postmenopausal period 3,5 years) the hormonal replacement therapy is carried out because of climacteric syndrome with Proginova (29 women), Cyclo-Proginova (25 women) and Climen (21 women). The preparations were nominated in a cyclic mode (average duration of treatment has made 5,6 cycles).
There is marked a high therapeutic effect as reduction of frequency of vegetovascular climacteric frustrations in Proginova application (83 % ), Cyclo- Proginova (84 %) and Climen (96%).
The application of Proginova, Cyclo-Proginova and Climen resulted in normalization of lipid spectrum of blood by 3 month of treatment, that was expressed in authentic decrease in initially raised cholesterin and cholesterin of low density, with increase of the contents of cholesterin fraction of high density.
The marked normalization of lipid spectrum as a result of hormonal replacement therapy can be considered as pathogenic influence directed on normalization in age - associated metabolic infringements in female organism.