Experimental models of type 1 diabetes | Zendy

Maria I. Yarmolinskaya | Zendy; Nelly Y. Andreyeva | Zendy; Elena I. Abashova | Zendy; Elena V. Misharina | Zendy

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Experimental models of type 1 diabetes

Author(s) -

Maria I. Yarmolinskaya,

Nelly Y. Andreyeva,

Elena I. Abashova,

Elena V. Misharina

Publication year - 2019

Publication title -

journal of obstetrics and women s diseases

Language(s) - English

Resource type - Journals

eISSN - 1684-0461

pISSN - 1683-9366

DOI - 10.17816/jowd682109-118

Subject(s) - medicine , type 2 diabetes , diabetes mellitus , disease , extrapolation , pathogenesis , animal model , bioinformatics , intensive care medicine , computational biology , endocrinology , biology , mathematics , mathematical analysis

This article describes currently used experimental animal models of type 1 diabetes. The literature data on the pathogenesis of clinical and morphological patterns of the disease and the possibility of extrapolation have been summarized in the review. In addition, the advantages and disadvantages of each of the models have been evaluated. Based on the reported results, it can be concluded that preclinical research is essential as fundamental basis for the investigation of type 1 diabetes mellitus.

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