Оpioid analgesics effects mechanisms on the particular reaction of endogenous opioid system of the body and the regulation of uterine activity during the nociceptive response in the experiment on rats | Zendy

Andrey Gennadyevich Kiselev | Zendy; А. А. Zaitsev | Zendy

Open Access

Оpioid analgesics effects mechanisms on the particular reaction of endogenous opioid system of the body and the regulation of uterine activity during the nociceptive response in the experiment on rats

Author(s) -

Andrey Gennadyevich Kiselev,

А. А. Zaitsev

Publication year - 2015

Publication title -

journal of obstetrics and women s diseases

Language(s) - English

Resource type - Journals

eISSN - 1684-0461

pISSN - 1683-9366

DOI - 10.17816/jowd64311-17

Subject(s) - medicine , opiate , nociception , opioid , morphine , endogenous opioid , pharmacology , endogeny , analgesic , enkephalin , anesthesia , receptor

This article presents the results of experimental investigation of opioid (opiate analgesics) influence on the nociceptive response of rat’s circulatory dynamics, breath and skeletal muscles tonus. The article demonstrates influence of opiate analgesics on intact and pregnant rat’s amplitude and frequency of uterine activity. The results of investigation of drug-induced effect of opiate analgesics in case of pregnant and in case of act of delivery model pain reaction were also described in this article.

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