Open AccessClinical value of determination of markers of a thrombophylia at patients with the complicated pregnancy in the anamnesis
Author(s) -
M.D. Andreeva
Publication year - 2015
Publication title -
žurnalʺ akušerstva i ženskihʺ boleznej
Language(s) - English
Resource type - Journals
eISSN - 1684-0461
pISSN - 1683-9366
DOI - 10.17816/jowd64213-17
Subject(s) - anamnesis , antithrombotic , medicine , miscarriage , thrombophilia , preeclampsia , pregnancy , d dimer , obstetrics , platelet , thrombosis , gynecology , genetics , biology
The results of the survey of 214 patients with the complicated pregnancy (a preeclampsia, a premature detachment of placenta, antenatal fetal death, miscarriage) in the anamnesis are presented in the article. We determined the level of molecular markers of a thrombophilia (TAT, D-dimer) and aggregation activity of platelets and carried out antithrombotic therapy to these women. It is shown that 47,7 % of such nonpregnant women and pregnant early terms have the high level of D-dimer, TAT - 46,7 %, aggregation activity of platelets - 52,6 %. Determination of the increased levels of molecular markers of a thrombophilia is the indication to application the antithrombotic therapy and allow to control efficiency of this therapy.