Open AccessSignificance of social and reproductive factors in mother-to child transmission of HIV
Author(s) -
Dariko A. Niauri,
Ekaterina Vladimirovna Musatova,
Andrey Viktorovich Kolobov,
Margarita Martirosyan,
В. Е. Карев,
Vsevolod Zinserling
Publication year - 2013
Publication title -
žurnalʺ akušerstva i ženskihʺ boleznej
Language(s) - English
Resource type - Journals
eISSN - 1684-0461
pISSN - 1683-9366
DOI - 10.17816/jowd62350-57
Subject(s) - medicine , pregnancy , human immunodeficiency virus (hiv) , obstetrics , transmission (telecommunications) , immunology , biology , genetics , electrical engineering , engineering
The retrospective analysis of pregnancy and delivery at 12 HIV-positive mothers who have performed mother-to-child transmission. In reference group — 11 HIV-positive women who have given birth to not-infected children. The study of placentae was done with immunohistochemical methods. For placentae of the infected children decrease of expression of CD31 and CD68 and increase of expression of TGF-в1 was typical. Leading factor in transmission of HIV is absence of ARVT.