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Influenza A virus reproduction in humanendometrial cells
Author(s) -
А. О. Дурнова,
Renata A. Kadyrova,
Darya Mikhaylovna Danilenko,
Maksim Igorevich Dyukov,
Vera Aleksandrovna Martyntseva,
Т. Д. Смирнова,
Mikhail Yuryevich Yeropkin,
О. И. Киселев
Publication year - 2013
Publication title -
journal of obstetrics and women s diseases
Language(s) - English
Resource type - Journals
eISSN - 1684-0461
pISSN - 1683-9366
DOI - 10.17816/jowd62223-28
Subject(s) - multiplicity of infection , menstrual cycle , influenza a virus , virus , medicine , viral replication , virology , microbiology and biotechnology , reproduction , immunology , biology , genetics , hormone
Study of replication of influenza A viruses (IAV) of A(H3N2) and A(H1N1)pdm subtypes in human endometrial cells was performed. It was shown that endometrial infection with IAV strongly depends on the multiplicity of infection and causes substantial changes in functional activities of these cells. Moreover endometrial cells of proliferative phase (day 8) were more sensitive to IAV infection than cells from secretory phase of menstrual cycle on day 19th.

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