Open AccessInfluenza A virus reproduction in humanendometrial cells
Author(s) -
А. О. Дурнова,
Дурнова Анна Олеговна,
Renata A. Kadyrova,
Кадырова Рената Анваровна,
Д М Даниленко,
Даниленко Дарья Михайловна,
Maksim Igorevich Dyukov,
Дюков Максим Игоревич,
Vera Aleksandrovna Martyntseva,
Мартынцева Вера Александровна,
Tatiana Smirnova,
Смирнова Татьяна Дмитриевна,
Mikhail Yuryevich Yeropkin,
Еропкин Михаил Юрьевич,
О. И. Киселев,
Киселев Олег Иванович
Publication year - 2013
Publication title -
žurnalʺ akušerstva i ženskihʺ boleznej
Language(s) - English
Resource type - Journals
eISSN - 1684-0461
pISSN - 1683-9366
DOI - 10.17816/jowd62223-28
Subject(s) - multiplicity of infection , menstrual cycle , influenza a virus , virus , medicine , viral replication , virology , microbiology and biotechnology , reproduction , immunology , biology , genetics , hormone
Study of replication of influenza A viruses (IAV) of A(H3N2) and A(H1N1)pdm subtypes in human endometrial cells was performed. It was shown that endometrial infection with IAV strongly depends on the multiplicity of infection and causes substantial changes in functional activities of these cells. Moreover endometrial cells of proliferative phase (day 8) were more sensitive to IAV infection than cells from secretory phase of menstrual cycle on day 19th.