Open AccessEvaluation of the efficiency and safety of therapy with calcium for pregnant women with symphysiopathia
Author(s) -
Anna Gennadyevna Dedul,
Дедуль Анна Геннадьевна,
Yelena Vitalyevna Mozgovaya,
Мозговая Елена Витальевна,
Т. И. Опарина,
Опарина Татьяна Ивановна,
Gulrukhsor Kh. Tolibova,
Толибова Гулрухсор Хайбуллоевна,
М. А. Petrosyan,
Петросян Мария Анатольевна,
V. I. Polyakova,
Полякова Виктория Олеговна
Publication year - 2013
Publication title -
žurnalʺ akušerstva i ženskihʺ boleznej
Language(s) - English
Resource type - Journals
eISSN - 1684-0461
pISSN - 1683-9366
DOI - 10.17816/jowd62210-16
Subject(s) - medicine , calcium , pregnancy , urine , magnesium , placenta , physiology , obstetrics , surgery , fetus , genetics , materials science , metallurgy , biology
According to the modern concepts, symphysiopathia usually occurs in the second half of pregnancy as a result of mineral metabolism violations. This complication of pregnancy mainly manifested as a pubic bone diastasis, pain in the bone of the pelvis and of the lower limbs, and cramps in the calf muscles. There are clinical manifestations of the symphysiopathia; indicators of calcium, magnesium and phosphorus in the blood and daily excretion of these minerals in the urine compared with those which have healthy pregnant women in the second and third trimesters. There is histological and immunohistochemical evaluation of placentas of patients on background treatment. The vast majority of pregnant women with symphysiopathia found increase in urinary calcium and magnesium in the urine remaining in the normal performance of mineral metabolism. According to the studies, the preparation of magnesium, calcium, and the local ultraviolet irradiation of symphysis pubis may reduce the clinical symptoms of symphysiopathia. The use of calcium supplements together with magnesium does not lead to excessive deposition of calcium salts in the placental tissue and improve metabolic function of placenta.