Open AccessCOMPARATIVE ANALYSIS OF THE EFFICIENCY OF THE INTRODUCTION OF METHODS OF THE EVALUATION OF QUALITATIVE PROPERTIES OF INFECTIOUS PATHOGENS INTO CLINICAL PRACTICE
Author(s) -
С. Г. Фоминых,
Фоминых Стелла Геннадьевна,
T. E Perepichkina,
Перепичкина Татьяна Евгеньевна
Publication year - 2017
Publication title -
èpidemiologiâ i infekcionnye bolezni
Language(s) - English
Resource type - Journals
eISSN - 2411-3026
pISSN - 1560-9529
DOI - 10.17816/eid42634
Subject(s) - antimicrobial , pseudomonas aeruginosa , klebsiella pneumoniae , formulary , staphylococcus aureus , microbiology and biotechnology , qualitative analysis , biology , medicine , bacteria , qualitative research , pharmacology , biochemistry , genetics , escherichia coli , gene , social science , sociology
In the paper there were studied qualitative properties of the dominant nosocomial wound and respiratory pathogens (Klebsiella pneumoniae, Pseudomonas aeruginosa and Staphylococcus aureus) over a 3-years period of the observation in hospital emergency medical care in two ways. The first pharmacoepidemiological approach was based on the estimated consumption of the main classes of antimicrobial agents and the occurrence of resistant isolates, the second method assumes a histogram reflecting statistical distribution of values of the inhibition diameter of zone of the growth of colonies of microorganisms. Two methods were proved to reveal an unidirectional trend, but the second method allows in more details to assess the dynamics of susceptibility/resistance of microorganisms depending on the type of pathogen and localization of the infection and to construct a formulary of antimicrobial agents on the basis of the actual consumption of drugs, but also from data obtained experimentally.