Open AccessPROSPECTIVE MONITORING OF AIRWAY COLONIZATION AS WAY TO VENTILATOR-ASSOCIATED PNEUMONIA PROPHYLAXIS
Author(s) -
Vladimir Aleksandrovich Sinikin,
Синикин Владимир Александрович,
Vladimir B. Beloborodov,
Белобородов Владимир Борисович
Publication year - 2017
Publication title -
èpidemiologiâ i infekcionnye bolezni
Language(s) - English
Resource type - Journals
eISSN - 2411-3026
pISSN - 1560-9529
DOI - 10.17816/eid40974
Subject(s) - ventilator associated pneumonia , intensive care medicine , pneumonia , medicine , colonization , airway , intensive care , intensive care unit , microbiology and biotechnology , biology , surgery
. Ventilator-associated pneumonia is the most common type of nosocomial infection. It’s characterized high mortality (24-76%), leads to increase of mechanical ventilation length, length of stay in intensive care units, significant increase of hospital length of stay and cost of care. The aim of this study was to perform the systematic analysis of the current literature devoted to the problem of airway bacterial colonization and ventilator-associated pneumonia (VAP) prophylaxis. Objectives of the study: the definition of the value of airway bacterial colonization in clinical practice, feasibility of airway bacterial colonization monitoring, prophylaxis, VAP diagnosis and prophylaxis which based on the bacterial colonization monitoring data. For the solution of the designated objectives in the scientific medical databases Medscape and Pubmed there was performed the search for the publications on subject headings, covering these problems. Conclusion. Airway bacterial colonization by potential infectious agent is a one of the key stage in VAP development. Prospective bacterial colonization monitoring (in addition to laboratory and instrumental analysis, clinical presentation) enable to get current microbiological data in prospective mode and to provide the targeted real-time antibacterial therapy in case of pneumonia onset. But at present this way is not convential and requires additional improvement. The guidelines to selection of time, type, technology and personalization VAP prophylaxis methods can be developed on basis of this technique.