Open AccessPostoperative bacteremia in patients of cardiac surgical profile
Author(s) -
L. I. Arefieva,
E. M. Gorskaya,
О А Савостьянова,
Т. С. Спирина,
L. Yu Romashkina,
Gabriélian Ni
Publication year - 2015
Publication title -
èpidemiologiâ i infekcionnye bolezni
Language(s) - English
Resource type - Journals
eISSN - 2411-3026
pISSN - 1560-9529
DOI - 10.17816/eid40947
Subject(s) - bacteremia , cefepime , medicine , antibiotics , cardiac surgery , antibiotic resistance , surgery , microbiology and biotechnology , biology , imipenem
Objective To determine the frequency of bacteremia and pathogens, mortality rate in patients after cardiac surgery. Materials and methods There was performed a retrospective analysis of bacteremia for 13 years from 2000 to 2012 after 8292 cardiac surgeries. Identification of the causative agents of bacteremia was carried out with the use of panels BD Crystal and database BBL Crystal MIND, the detection of susceptibility of microbes to antibiotics by disk diffusion method in accordance with the standards NCCLS. Results The frequency of bacteremia decreased over the study period, from 6.8% in 2000 -2004 to 3.6% in 2010 - 2012. Bacteremia accounted for the bulk of postoperative infectious complications (PIC) - 77.8% - 80.4%. There is given the characteristic of the frequency of isolation in bacteremia with Gr+ and Gr- microbes, as well as the severity of PICs. In the spectrum of blood in bacteremias coagulase negative staphylococcocci prevailed at the background of the general dominance of Gr+ microflora. There was noted the resistance of gram-positive microflora to beta-lactam antibiotics and multiple resistance to antibiotics of non-fermenting bacteria except Polymyxine, Tigacil, and Cefepime, sulperazon