Open AccessEdema and swelling of the brain in the neuroinfections
Author(s) -
Yu. Ya. Vengerov,
Венгеров Юрий Яковлевич,
М. В. Нагибина,
Нагибина Маргарита Васильевна,
O. E Volkova,
Волкова Ольга Евгеньевна,
E. V Belikoya,
Беликова Елена Владимировна,
L. B Baikova,
Байкова Лидия Борисовна,
D. V Chernichov,
Чернышев Дмитрий Владимирович,
Т. Д. Смирнова,
Смирнова Т. Ю,
О. А. Тишкевич,
Тишкевич Олег Александрович,
Yu. G. Parkhomenko,
Пархоменко Юрий Георгиевич
Publication year - 2015
Publication title -
èpidemiologiâ i infekcionnye bolezni
Language(s) - English
Resource type - Journals
eISSN - 2411-3026
pISSN - 1560-9529
DOI - 10.17816/eid40857
Subject(s) - swelling , medicine , edema , brain edema , pathology
The course and outcome of edema and swelling of the brain (OSB) essentially depend on many factors, including the feature of the pathogenesis of the disease associated with the factors ofpathogenicity of the causative agent. There was developed the multivariate mathematical analysis of the clinical picture of OSB with the using of an alternative algorithm of the distributions offrequencies of symptoms in differentiated groups of patients with the presence of OSB and without of OSB signs of this complication that permitted to make more accurately diagnose of OSB and judge the effectiveness of the taken therapy. The lack of clinical effect of antibiotic therapy is caused among other things the low bioavailability of the pathogen. BBB is not associated with an HLB so attempts on the base of the measurement of the spinal fluid pressure to detect the presence and severity of OSB have not been scientifically justified. The analysis of CSF indices - lactate, protein, glucose, D-DF, pH level against the background of OSB will allow to avoid unsound replacement of etiotropic drugs