Open AccessNew data on the pathogenicity of genotype of Rickettsia sibirica subspecies BJ-90
Author(s) -
Н. В. Рудаков,
С. Н. Шпынов,
Т. А. Решетникова,
Н. А. Пеньевская,
Н В Абрамова,
Л. В. Кумпан
Publication year - 2014
Publication title -
èpidemiologiâ i infekcionnye bolezni
Language(s) - English
Resource type - Journals
eISSN - 2411-3026
pISSN - 1560-9529
DOI - 10.17816/eid40815
Subject(s) - subspecies , biology , serology , genotype , virology , pathogenicity , spotted fever , rickettsia , vero cell , microbiology and biotechnology , antibody , gene , genetics , virus , zoology
New data about pathogenicity of Rickettsia sibirica subspecies BJ-90 were obtained. Rickettsial strains of this subspecies from the Primorye region were pathogenic for guinea pigs and chick embryos, multiplied in cell cultures Vero E6. Antibodies against Rickettsia sibirica subspecies BJ-90 in ELISA were detected in the Omsk region in patients with clinical manifestations after bites of ticks. Analysis of available data indicates to the likely pathogenicity of this genotype for human. Due to the low cross reactivity of R. sibirica subsp. BJ-90 and R. sibirica subsp. sibirica in combined foci serological diagnosis of tick-borne rickettsioses in ELISA should be carried out with antigens of both subspecies of Rickettsia sibirica.