Hepatitis C in infection with recombinant strain RF2k/1b of the virus: clinical course and therapy
Author(s) -
Л. И. Николаева,
Г. В. Сапронов,
А.В. Колотвин,
Е И Самохвалов,
E. A. Leybman,
L. М. Samokhodskaya
Publication year - 2014
Publication title -
epidemiology and infectious diseases
Language(s) - English
Resource type - Journals
eISSN - 2411-3026
pISSN - 1560-9529
DOI - 10.17816/eid40805
Subject(s) - recombinant dna , virology , medicine , virus , hepatitis c virus , antiviral therapy , russian federation , strain (injury) , chronic hepatitis , hepatitis , biology , biochemistry , gene , business , economic policy
Intergenotype recombinant RF2k/1b of hepatitis C virus was firstly detected in 2002 in the Russian Federation. In our study patients, infected with this recombinant, had high indices of liver fibrosis and did not achieve a sustained viral response to standard double therapy with exception of one participant. There are discussed and proposed options for treatment and diagnosis of these patients.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom