Open AccessHepatitis C in infection with recombinant strain RF2k/1b of the virus: clinical course and therapy
Author(s) -
Л. И. Николаева,
Г. В. Сапронов,
А.В. Колотвин,
Е И Самохвалов,
Elena Leybman,
L М Samokhodskaya
Publication year - 2014
Publication title -
èpidemiologiâ i infekcionnye bolezni
Language(s) - English
Resource type - Journals
eISSN - 2411-3026
pISSN - 1560-9529
DOI - 10.17816/eid40805
Subject(s) - recombinant dna , virology , medicine , virus , hepatitis c virus , antiviral therapy , russian federation , strain (injury) , chronic hepatitis , hepatitis , biology , biochemistry , gene , business , economic policy
Intergenotype recombinant RF2k/1b of hepatitis C virus was firstly detected in 2002 in the Russian Federation. In our study patients, infected with this recombinant, had high indices of liver fibrosis and did not achieve a sustained viral response to standard double therapy with exception of one participant. There are discussed and proposed options for treatment and diagnosis of these patients.