Open AccessSeasonal fluctuations of H.Pylori markers in patients with acute viral hepatitis
Author(s) -
Olga Belaia,
Белая Ольга Федоровна,
S. N Zuevskaya,
Зуевская Светлана Николаевна,
O. A Paevskaya,
Паевская Ольга Александровна,
Yu. V. Yudina,
Юдина Юлия Владимировна,
Е. В. Волчкова,
Волчкова Елена Васильевна,
Son-Il Pak,
Пак Сергей Григорьевич
Publication year - 2014
Publication title -
èpidemiologiâ i infekcionnye bolezni
Language(s) - English
Resource type - Journals
eISSN - 2411-3026
pISSN - 1560-9529
DOI - 10.17816/eid40770
Subject(s) - helicobacter pylori , etiology , antigen , viral hepatitis , medicine , feces , immune system , immunology , gastroenterology , virology , biology , microbiology and biotechnology
Under investigation of the dynamics of pathogenicity factors H. pylori (LPS/O-antigen markers VacA and high molecular weight proteins (HMWP) (including CagA) in the body ofpatients with acute viral hepatitis (AVH) of different etiology there were established seasonal patterns in feces and serum circulating immune complexes (CIC): LPS/O-antigen markers and H. pylori VacA included in CIC. The detection rate and levels of markers of H. pylori in patients who had AVH in January-April exceeded similar indices in patients whi had AVH in May-August. We believe that these data should be considered in the assessment of the results of the diagnosis ofH. pylori and results of eradication therapy.