Open Access
THE CLINICAL COURSE OF INVASIVE CANDIDIASIS IN HIV-INFECTED PATIENTS
Author(s) -
I. P. Charushina,
N. N. Vorobiova,
S. B. Lyapustin,
A. G. Zemskov
Publication year - 2013
Publication title -
èpidemiologiâ i infekcionnye bolezni
Language(s) - English
Resource type - Journals
eISSN - 2411-3026
pISSN - 1560-9529
DOI - 10.17816/eid40756
Subject(s) - invasive candidiasis , medicine , human immunodeficiency virus (hiv) , immunology , sepsis , disease , immunodeficiency , immune system , intensive care medicine , antifungal , dermatology , fluconazole
The article presents the results of observation of 21 patients with invasive candidiasis, developed on the background of HIV infection for the period 2007-2013. The features of clinical course of the disease and the risk factors for its occurrence are described. The clinical ркЫп of invasive candidiasis in HIV-infected patients is similar to the clinical picturde seen in bacterial sepsis, it is characterized by the severe course and the high fatality. The risk factors are the pronounced immune deficiency, the absence of antiretroviral ^тру and the presence of 2 or more foci of the s^etAnal candidiasis. The diagnosis of the hematogenous dissemination should be carried out in all HIV-infected patients with the reference symptoms.