Open AccessIMMUNOLOGICAL PARAMETERSAND BLOOD LYMPHOCYTE ENZYME PROFILE IN BABIES WITH RECURRENT RESPIRATORY INFECTIONS
Author(s) -
Л. М. Куртасова,
Т. В. Лубнина
Publication year - 2012
Publication title -
èpidemiologiâ i infekcionnye bolezni
Language(s) - English
Resource type - Journals
eISSN - 2411-3026
pISSN - 1560-9529
DOI - 10.17816/eid40697
Subject(s) - immunology , immune system , respiratory system , peripheral blood , lymphocyte , intracellular , enzyme , immune status , humoral immunity , nad+ kinase , medicine , biology , biochemistry
84 babies aged 1 to 3 years suffered from recurrent respiratory infections were studied. Cellular and humoral immunological parameters, phagocytic activity of neutrophils and activities of NAD- and NADP-dependent dehydrogenases in peripheral blood lymphocytes were estimated. Immunophenotypic changes found in blood lymphocytes included decreased IgA levels and a tendency of serum IgM to increase. An elevated level of circulating immune complexes was revealed in the blood serum. Decreased levels active neutrophils in the peripheral blood were detected. In the enzyme status of blood lymphocytes such changes as increased levels of synthetic processes and intense intracellular energy metabolism can be observed.