Open AccessThe first experience of combination therapy of loaosis in Russian female tourist who visited Equatorial Guinea
Author(s) -
А. М. Бронштейн,
Н А Малышев,
С. Н. Жаров,
В И Лучшев,
O. Yu Rakhimova,
Yu. A Legonkov
Publication year - 2012
Publication title -
èpidemiologiâ i infekcionnye bolezni
Language(s) - English
Resource type - Journals
eISSN - 2411-3026
pISSN - 1560-9529
DOI - 10.17816/eid40651
Subject(s) - albendazole , ivermectin , medicine , eosinophilia , diethylcarbamazine , serous fluid , filariasis , surgery , pediatrics , helminths , immunology , veterinary medicine
A case of loaosis in a female tourist from the Bryansk region, which visited Equatorial Guinea, has been described. The clinical picture of the disease was characterized by recurrent ‘tumor de Calabar’ (ambulant edema) in different parts of the body, migration of helminth beneath of eye serous membrane and high eosinophilia. The patient was successfully cured with the use of combination therapy consisting of sequential taking albendazole and ivermectin treatment. For the prevention of adverse reactions during all the period of treatment with albendazole and ivermectin the patient received glucocorticosteroid medication. 2-year dispensary observation showed adequately treatment of the patient, the absence of relapse and normalization of eosinophil count in the peripheral blood. We discuss the objective complexity of the parasitological confirmation of loaosis and the problem of prevention of tropical diseases in backpacking tourists.