Researching the mechanisms of gene РНО3 regulation de pending on nitrogen source in medium in yeast Sacharomyces cere visiae | Zendy

Vladimir A. Savinov | Zendy; Anastasia I Fizikova | Zendy; Andrey M. Rumyantsev | Zendy; Elena V. Sambuk | Zendy

Open Access

Researching the mechanisms of gene РНО3 regulation de pending on nitrogen source in medium in yeast Sacharomyces cere visiae

Author(s) -

Vladimir A. Savinov,

Anastasia I Fizikova,

Andrey M. Rumyantsev,

Elena V. Sambuk

Publication year - 2011

Publication title -

ecological genetics

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.148

H-Index - 3

eISSN - 2411-9202

pISSN - 1811-0932

DOI - 10.17816/ecogen9470-78

Subject(s) - yeast , gene , saccharomyces cerevisiae , gene expression , biology , promoter , regulation of gene expression , repressor , transcriptional regulation , ubiquitin ligase , microbiology and biotechnology , biochemistry , genetics , ubiquitin

Delicate regulation of gene expression is performed through transcriptional factors competition for promoters that provides punctual cell response to environmental changes. Gene PHO3 of yeast S. cerevisiae encodes the constitutive acid phosphatase. In this work we researched genetic control of the gene PHO3 expression in response to nitrogen source in medium. PHO3 expression level was proved to decrease while yeast using poor nitrogen source like urea. Possible regulatory mechanisms for gene PHO3 were revealed involving repressor of nitrogen regulated genes Gzf3p and ubiquitin ligase Rsp5p

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research