Open AccessEffect of LIM kin ase 1 is oform ratio on Drosophil a mel anogaster courtship behavior: a complex approach
Author(s) -
A. N. Kaminskaya,
Е. А. Никитина,
Tatyana L Payalina,
Dmitry Molotkov,
Г. А. Захаров,
А. В. Попов,
Е. В. Савватеева-Попова
Publication year - 2011
Publication title -
èkologičeskaâ genetika
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.148
H-Index - 3
eISSN - 2411-9202
pISSN - 1811-0932
DOI - 10.17816/ecogen943-14
Subject(s) - biology , courtship , courtship display , memory formation , mutant , drosophila melanogaster , genetics , microbiology and biotechnology , neuroscience , gene , zoology , hippocampus
LIMK1 - is the key enzyme of actin remodeling which controls dendritic spine morphology necessary for synaptic plasticity during learning and memory formation. Conditioned courtship suppression paradigm and a set-up for communicative sound production during courtship were used to asses learning acquisition and memory formation in four Drosophila strains polymorphic for the limk1 gene harbored by the agnostic locus: the wild type strains Canton-S, Berlin, Oregon-R and the mutant аgnts3. Behavioral performances were compared to the brain content and ratio of two LIMK1 isoforms in these Drosophila strains.