Open AccessEvaluation of antigenotoxic effects of juices of plants Chelidonium majus L., Plantago major L. и Tussilago farfara L.
Author(s) -
Diana G Fatykhova,
Nazira S. Karamova,
Yoldyz R Abdrahimova,
О. N. Ilinskaya
Publication year - 2010
Publication title -
èkologičeskaâ genetika
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.148
H-Index - 3
eISSN - 2411-9202
pISSN - 1811-0932
DOI - 10.17816/ecogen8256-65
Subject(s) - chelidonium , genotoxicity , traditional medicine , biology , herb , plantago ovata , food science , botany , chemistry , medicinal herbs , toxicity , medicine , organic chemistry
The antigenotoxic effects of juices of three medicinal plants, Chelidonium majus L., Plantago major L. and Tussilago farfara L. has been studied in two bacterial tests — SOS chromotest and Rec assay. Antigenotoxic effect was determined against known genotoxic substances — nalidixic acid in SOS chromotest and furacilin in Rec assay. Preparations obtained from the leaves of Ch. majus L. exhibited significant antigenotoxic effect in both the SOS chromotest and the Rec assay. It was shown that dilution of the herb juice of T. farfara L resulted in high bioantimutagenic activity in SOS chromotest. P. major L. preparations did not display statistically significant antigenotoxic activity in the both tests used. Possible mechanisms of antigenotoxic effects of Ch. majus L. and T. farfara L. plants obtained are discussed.