Open AccessPost-stress chemosignals affect cells from immunocompetent organs in laboratory mice of three inbred strains
Author(s) -
Е. В. Даев,
Б. П. Суринов,
A. V. Dukelskaya
Publication year - 2008
Publication title -
èkologičeskaâ genetika
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.148
H-Index - 3
eISSN - 2411-9202
pISSN - 1811-0932
DOI - 10.17816/ecogen6127-33
Subject(s) - biology , inbred strain , spleen , bone marrow , mitosis , pheromone , ratón , immunology , genetics , microbiology and biotechnology , gene
Quantity of antibody producing cells and changes in bone marrow dividing cells of mouse males were studied after the exposure with chemosignals from intact or stressed donor mouse males. Inbred CBA, BALB/c and C57BL/6 strains were used. It is shown that excreted volatiles decrease quantity of antibody producing cells in spleen and at the same time raise the level of mitotic disturbances in bone marrow cells of recipient mice. Pheromone effect depends on genotype and physiological state of the recipients. For the first time we describe here the influence of mouse female pheromone 2,5-dimethylpyrazine on analyzed features. Biological meaning of the discovered effects is discussed.