ANALYSIS OF ASSOCIATION OF LIPID METABOLISM GENES POLYMORPHISM WITH BMI, WAIST CIRCUMFERENCE AND BLOOD LIPIDOGRAM PARAMETERS IN WOMEN | Zendy

Irina V Tarkovskaia | Zendy; Oleg S. Glotov | Zendy; Ekaterina Y Ditkina | Zendy; Elena S. Vashukova | Zendy; Аndrey S. Glotov | Zendy; Roman Vladimirovich Kurilov | Zendy; Irina V Pugacheva | Zendy; Olga L Belonog | Zendy; Ирина Александровна Махрова | Zendy; М. В. Асеев | Zendy; Т. Э. Иващенко | Zendy; В. С. Баранов | Zendy

Open Access

ANALYSIS OF ASSOCIATION OF LIPID METABOLISM GENES POLYMORPHISM WITH BMI, WAIST CIRCUMFERENCE AND BLOOD LIPIDOGRAM PARAMETERS IN WOMEN

Author(s) -

Irina V Tarkovskaia,

Oleg S. Glotov,

Ekaterina Y Ditkina,

Elena S. Vashukova,

Аndrey S. Glotov,

Roman Vladimirovich Kurilov,

Irina V Pugacheva,

Olga L Belonog,

Ирина Александровна Махрова,

М. В. Асеев,

Т. Э. Иващенко,

В. С. Баранов

Publication year - 2012

Publication title -

ecological genetics

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.148

H-Index - 3

eISSN - 2411-9202

pISSN - 1811-0932

DOI - 10.17816/ecogen10466-76

Subject(s) - waist , circumference , body mass index , polymorphism (computer science) , medicine , biology , logistic regression , restriction fragment length polymorphism , cholesterol , obesity , genetics , endocrinology , genotype , gene , geometry , mathematics

Using the PCR-RFLP method we have studied polymorphism of 36 genes involved in lipid metabolism in 212 women, residents of the North-West Region of Russia (St. Petersburg), aged 18 to 77. We found an association of polymorphism in several candidate genes with body mass index, waist circumference, total cholesterol level, low density lipoprotein cholesterol level and very low density lipoprotein cholesterol level. We propose a logistic regression model for a primary assessment of these parameters in women based on corresponding genetic markers tests.

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