Open AccessTO THE QUESTION OF DIFFERENTIAL DIAGNOSIS OF T CELL SKIN LYMPHOMAS
Author(s) -
O. Yu Olisova,
D. R Amshinskaya,
Ekaterina M. Anpilogova
Publication year - 2019
Publication title -
rossijskij žurnal kožnyh i veneričeskih boleznej
Language(s) - English
Resource type - Journals
eISSN - 2412-9097
pISSN - 1560-9588
DOI - 10.17816/dv42940
Subject(s) - mycosis fungoides , medicine , pathology , dermatology , differential diagnosis , lymphoma , disease , cutaneous t cell lymphoma , immunohistochemistry , incidence (geometry) , physics , optics
Cutaneous T cell lymphomas (CTCL) are a clinically and morphologically heterogeneous group of cutaneous malignant tumors, caused by monoclonal proliferation of lymphoid tissue cells in the skin. They are responsible for about 80% of all primary cutaneous lymphomas, while cutaneous lymphomas are responsible for 2% of all dermatological diseases. The incidence of CTCL is now increasing all over the world. For this reason, CTCL has to be diagnosed on the early stage to improve course of the disease. Mycosis fungoides, the most frequent CTCL variant, is usually diagnosed basing on clinical, histological, immunohistochemical and molecular findings. However, it can imitate other chronic dermatoses, which makes it difficult to diagnose. The article presents a review of the current literature data on new diagnostic markers of cutaneous T-cell lymphomas.