Open AccessCLINICAL AND MORPHOLOGICAL CHARACTERISTICS AND PROGNOSTIC SIGNIFICANCE OF THE CONTENTS OF PD-ECGF, TGF-β, KI67 IN ENDOMETRIUM AT LARGE UTERINE LEIOMYOMA
Author(s) -
S I Askolskaya,
E A Kogan,
Yu. V. Popov,
M A Solomakhina,
N.M. Fayzullina
Publication year - 2016
Publication title -
kliničeskaâ praktika
Language(s) - English
Resource type - Journals
eISSN - 2618-8627
pISSN - 2220-3095
DOI - 10.17816/clinpract7129-33
Subject(s) - endometrium , uterine fibroids , uterus , leiomyoma , uterine leiomyoma , medicine , gynecology , transforming growth factor , pathology
The endometrium may be the most convenient object of forecasting the development of the large uterine fibroid, as the object is available in the diagnosis of diseases of the uterus, changes in its cytokine profile linked with the growth of uterine fibroid. Immunohistochemically identification of high expression of Ki 67, TGF-, PD-ECGF in the endometrium allows to predict the development of large uterine fibroids.