Open AccessThe incidence of alleles and genotypes of polymorphic genes leptin G(-2548) A, adiponectin G(276) T and receptor adiponectin A(+219) T in patients with psoriasis alimentary obesity
Author(s) -
И В Рычкова,
О. А. Притуло,
Konstantin Maliy
Publication year - 2019
Publication title -
vestnik rossijskoj voenno-medicinskoj akademii
Language(s) - English
Resource type - Journals
eISSN - 2687-1424
pISSN - 1682-7392
DOI - 10.17816/brmma25913
Subject(s) - adiponectin , leptin , medicine , genotype , allele , endocrinology , obesity , body mass index , biology , gene , genetics , insulin resistance
Investigated prevalence of alleles and genotypes G(-2548)A (rs7799039) gene leptin and G(276)T (rs1501299) of the adiponectin and A(+219)T (rs11061971) adiponectin receptor 2 in patients with psoriasis with abdominal obesity. The frequency of the allele A of the promoter region of the G(-2548) A polypeptide leptin gene in 99/226 (43,8%) patients with a body mass index ≥30 kg / m2 was found to be higher than in69/228 (30,3% ) patients with a body mass index