Open AccessModern approaches to evaluating the effectiveness of treatment of chronic heart failure
Author(s) -
Н П Потехин,
А. Н. Фурсов,
С. П. Казаков,
S.B. Putkov,
O.R. Pestovskaya,
N. B. Lyapkova,
Е. Г. Захарова,
T. G. Makeeva,
А В Верещагина
Publication year - 2019
Publication title -
vestnik rossijskoj voenno-medicinskoj akademii
Language(s) - English
Resource type - Journals
eISSN - 2687-1424
pISSN - 1682-7392
DOI - 10.17816/brmma20693
Subject(s) - valsartan , medicine , heart failure , cardiology , pharmacotherapy , intensive care medicine , blood pressure
The efficacy of therapy for patients with chronic heart failure, a new combination drug valsartan/sacubitrile according to the levels of biomarkers ST2 and NT-proBNP was evaluated. In all patients of the study group, valsartan/sacubitrile therapy improved the NYHA functional class, in the control group - only in 75%. The dynamics of indicators of biomarkers ST2 and NT-proBNP coincided with the improvement of the clinical status of patients against the background of therapy, and to a greater extent this trend reflects the indicator NT-proBNP.