Modern approaches to evaluating the effectiveness of treatment of chronic heart failure | Zendy

N. P. Potekhin | Zendy; А. Н. Фурсов | Zendy; С. П. Казаков | Zendy; S B Putkov | Zendy; O.R. Pestovskaya | Zendy; N. B. Lyapkova | Zendy; Е. Г. Захарова | Zendy; T. G. Makeeva | Zendy; А В Верещагина | Zendy

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Modern approaches to evaluating the effectiveness of treatment of chronic heart failure

Author(s) -

N. P. Potekhin,

А. Н. Фурсов,

С. П. Казаков,

S B Putkov,

O.R. Pestovskaya,

N. B. Lyapkova,

Е. Г. Захарова,

T. G. Makeeva,

А В Верещагина

Publication year - 2019

Publication title -

bulletin of the russian military medical academy

Language(s) - English

Resource type - Journals

eISSN - 2687-1424

pISSN - 1682-7392

DOI - 10.17816/brmma20693

Subject(s) - valsartan , medicine , heart failure , cardiology , pharmacotherapy , intensive care medicine , blood pressure

The efficacy of therapy for patients with chronic heart failure, a new combination drug valsartan/sacubitrile according to the levels of biomarkers ST2 and NT-proBNP was evaluated. In all patients of the study group, valsartan/sacubitrile therapy improved the NYHA functional class, in the control group - only in 75%. The dynamics of indicators of biomarkers ST2 and NT-proBNP coincided with the improvement of the clinical status of patients against the background of therapy, and to a greater extent this trend reflects the indicator NT-proBNP.

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