Open AccessSHORT-TERM OUTCOMES OF SURGICAL TREATMENT OF PANCREATIC NEUROENDOCRINE TUMORS ASSOCIATED WITH THE SYNDROME OF MULTIPLEENDOCRINE NEOPLASIA TYPE 1
Author(s) -
А. В. Егоров,
А. В. Егоров,
Ivan Vasilyev,
И. А. Васильев,
Ivan Ivashov,
Ivan Ivashov,
Anmol Thakur,
А С Тхакур
Publication year - 2019
Publication title -
vestnik rossijskoj voenno-medicinskoj akademii
Language(s) - English
Resource type - Journals
eISSN - 2687-1424
pISSN - 1682-7392
DOI - 10.17816/brmma13049
Subject(s) - men1 , medicine , multiple endocrine neoplasia , neuroendocrine tumors , endocrine system , pancreas , surgery , hormone , biochemistry , chemistry , gene
Background: pancreaticneuroendocrine tumors occur in almost all patients with multiple endocrine neoplasia type 1 (MEN1) and are a major cause of death. Surgical resection is the only potentially curative therapy for pNETs, otherwise various endocrine syndromesdevelop threatening the patient's life. Aim: to evaluate the short-term results of surgical management of patients with pancreatic neuroendocrine tumors with MEN1. Materials and methods: by last 20 years, 40 patients with pancreatic neuroendocrine tumors within MEN1 were operated. Results: in the early postoperative period,according to the classification of Clavien-Dindo, complications occurred in 12 (26%) patients. The following types of complications were diagnosed: IIIa in 6 patients; IIIb - in 2; type V in 4 patients. Complications of types I, II and IV were not identified. Conclusion: less percentage of postoperative complications is achieved by performing organ-preserving operations, after precise imaging diagnose, due to minimal intraoperative pancreatic injury.