Open AccessPossibilities of use of arc-type discharge low-temperature air plasma of atmospheric pressure for burn wound treatment
Author(s) -
E V Zinovyev,
V N Tsygan,
M S Asadulayev,
O V Borisov,
I M Lopatin,
S A Lukyanov,
Ilya V. Artsimovich,
M B Paneyakh,
D V Kostyakov,
S N Kravtsov,
V V Zubov,
K F Osmanov
Publication year - 2018
Publication title -
vestnik rossijskoj voenno-medicinskoj akademii
Language(s) - English
Resource type - Journals
eISSN - 2687-1424
pISSN - 1682-7392
DOI - 10.17816/brmma12315
Subject(s) - atmospheric pressure , atmospheric pressure plasma , plasma , atmospheric air , low pressure area , negative pressure wound therapy , plasma medicine , wound healing , composite material , materials science , chemistry , surgery , medicine , pathology , atmospheric sciences , meteorology , physics , alternative medicine , quantum mechanics , geology
Results of experimental assessment of efficiency of use of low-temperature air plasma of the arc category of atmospheric pressure at treatment of burns of skin of the III degree in small laboratory animals are given. It is established that use of low-temperature air plasma of the arc-type discharge of atmospheric pressure allows to accelerate terms of final healing of wounds for 49% (p0,05), to reduce development frequency in them purulent inflammation by 45,5% (p0,01). Positive influence of air and plasma processing on dynamics of the area of a hem which after single influence by 35 days is reduced for 67% is revealed (p0,01). The analysis of a histologic picture confirms acceleration of formation of an extracellular matrix and epitelization against the background of impact of an air and plasma stream on wounds. Processing of a wound of low-temperature air plasma of the arc category of atmospheric pressure after an early surgical escharotomy allows to form on a wound surface a so-called nanofilm of a layer the coagulated proteins of wound exudate and cellular fragments which has selective vapor permeability, reduces an rate of wounds pathogenic infection, prevents drying and as a result, allows to reduce the frequency of development of purulent complications and extent of zones of a secondary necrosis. Influence of a stream of low-temperature air plasma of the arc-type discharge of atmospheric pressure allows to optimize significantly processes of reparative regeneration in a zone of a deep burn of skin at a stage of preparation for their surgical treatment.