Open AccessTHE POSSIBILITY OF USING THE POLYMER FOR THE TREATMENT OF FULL NANOBIOCOMPOSITES SKIN DEFECTS
Author(s) -
E. V. Zinoviev,
Marat S Asadulaev,
D. V. Kostyakov,
К. Ф. Османов,
Roman G Stoyanovskiy,
Natal'ya V Smirnova,
Anton S. Shabunin,
Sergey A Luk'yanov
Publication year - 2017
Publication title -
vestnik rossijskoj voenno-medicinskoj akademii
Language(s) - English
Resource type - Journals
eISSN - 2687-1424
pISSN - 1682-7392
DOI - 10.17816/brmma12164
Subject(s) - histogenesis , chitosan , hyaluronic acid , materials science , polymer , regeneration (biology) , wound healing , biomedical engineering , surgery , medicine , dermatology , composite material , chemistry , organic chemistry , anatomy , pathology , biology , immunohistochemistry , microbiology and biotechnology
The results of the experimental evaluation of the effectiveness of wound dressings based on chitosan nanofibres and copolyamide with treatment of full mechanical skin wounds. To develop their own original technique of mechanical reproduction all layers of the skin wounds in the experiment. It was found that application of wound dressings based on aliphatic copolyamide and chitosan can significantly optimize reparative regeneration processes in the area all layers of the skin defect, thus reducing the time stated scab rejection and wound healing, respectively, 7.5 and 11.2 days (p 0,05). It is shown that the use of coatings based on hyaluronic acid hydrogel is also accompanied by a significant acceleration in the zone histogenesis all layers of the blemishes, shortening the healing period of the final 21% (p 0,05) (4 figs, 1 table, bibliography: 14 refs).