A new combined method for treating involutive changes in the periorbital region

Objective. To solve the problem of correction of involutive changes in the periorbital region, it is necessary to approach from the position of a multidisciplinary approach, since a wide range of problems that need to be solved is possible in this localization. Laser therapy methods have been the standard for correcting age-related changes for many years. However, many questions of combined methods remain open, so the search and development of the most effective protocols for their use is an urgent task of modern medicine. Purpose of the study. Based on the study of the results of clinical efficacy and taking into account the indicators of quality characteristics of the skin, as well as microcirculation, to develop a combined method for correcting involutive skin changes in the periorbital region in young and middle-aged patients using fractional Nd:YAG and CO2 laser in combination with lower transconjunctival blepharoplasty. Material and methods. The study involved 108 patients with involutive changes in the skin of the lower eyelid. Depending on the method of treatment, patients were divided into groups. Special methods were used in the study: the study of qualitative characteristics of the skin (cutometry, TEVA-metry, corneometry), microcirculatory processes using laser flowmetry. Results. The effectiveness of the developed combined method is based on a pronounced positive effect on the active and passive mechanisms of hemodynamics at all levels of the microcirculatory bed, which is confirmed by an increase in the integral indicator of MC by 45.92% against 26.35% and 5.77% in the comparison groups, while the coefficient of variation of the indicator of MC increased by 33.02% against 24.19% and 6.46% after applying the components of the method. The use of the combined treatment method leads to the restoration of skin quality characteristics: the moisture index increased by 27% (p 0.05) compared to 14.1%, 7.8% in groups 1 and 2, respectively, the transepidermal water loss index decreased by 47% (p 0.05) (compared to 35%, 12.7% in groups 1 and 2, respectively), the ua/Uf elasticity index increased by 23.2% (p 0.05) (compared to 18.4%, 16.4% in groups 1 and 2, respectively). Conclusion. On the basis of the conducted research it can be concluded that the developed combined method of treatment is highly effective.