Open AccessPrevention of post-radiation damage to the bladder with medicinal plants in patients with locally advanced forms of cervical cancer
Author(s) -
С. В. Корепанов,
С. В. Корепанов,
А. Ф. Лазарев,
А Ф Лазарев,
М. Г. Николаева,
М. Г. Николаева,
В. Д. Петрова,
Петрова Валентина Дмитриевна
Publication year - 2020
Publication title -
rossijskij onkologičeskij žurnal
Language(s) - English
Resource type - Journals
eISSN - 2412-9119
pISSN - 1028-9984
DOI - 10.17816/1028-9984-2020-25-2-61-66
Subject(s) - medicine , cervical cancer , radiation therapy , bladder cancer , randomized controlled trial , cancer , clinical trial , surgery
Objective: to study the effect of phytotherapy on the frequency and extent of post-radiation injuries in patients with locally advanced forms of cervical cancer who received chemo-radiation treatment.
Material and methods: a randomized clinical trial was conducted, including 2 groups of patients aged 2464 years with a morphologically confirmed diagnosis of locally advanced (IIbIIIb) cervical cancer. The main group consisted of 350 patients who received standard chemo-radiation therapy against the background of therapy with medicinal plants using the original patented method, and a comparison group of 402 patients who received only standard special treatment.
Results: accompanying therapy with medicinal plants reduces the risk of early post-radiation complications of the bladder (erosive cystitis) in patients of the main group by 1.4 times [2.9 (3.72.1) % vs. 4.0 (5.03.0)% ; p = 0.0001]; late (5 years after treatment) 2.9 times [0.9 (0.960.84) % vs. 2.6 (3.71.5) %; p = 0.0001].