
The role of inositol deficiency in the etiology of polycystic ovary syndrome disorders
Author(s) -
Artur Jakimiuk,
Jacek Szamatowicz
Publication year - 2014
Publication title -
ginekologia polska
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.4
H-Index - 21
eISSN - 2543-6767
pISSN - 0017-0011
DOI - 10.17772/gp/1691
Subject(s) - polycystic ovary , inositol , insulin resistance , medicine , endocrinology , ovary , insulin , second messenger system , etiology , hormone , receptor
Inositol acts as a second messenger in insulin signaling pathway Literature data suggest inositol deficiency in insulin-resistant women with the polycystic ovary syndrome. Supplementation of myo-inisitol decreases insulin resistance as it works as an insulin sensitizing agent. The positive role of myo-inositol in the treatment of polycystic ovary syndrome has been of increased evidence recently The present review presents the effects of myo-inositol on the ovarian, hormonal and metabolic parameters in women with PCOS.