Open AccessPattern prescription drugs for systemic hypertension in primary health care: systematic review and meta-analysis
Author(s) -
Edilson Almeida de Oliveira,
Iris Heloísa Pereira Guerra,
Débora Canassa Volpato,
Rogério Toshiro Passos Okawa,
Kesia PalmaRigo,
Thaís da Silva Santos,
Jorge Juarez Vieira Teixeira
Publication year - 2021
Publication title -
saúde e pesquisa
Language(s) - English
Resource type - Journals
eISSN - 2176-9206
pISSN - 1983-1870
DOI - 10.17765/2176-9206.2021v14n1.e7743
Subject(s) - medical prescription , medicine , meta analysis , systematic review , angiotensin receptor blockers , primary care , combination therapy , primary health care , medline , alternative medicine , family medicine , intensive care medicine , angiotensin converting enzyme , pharmacology , blood pressure , environmental health , pathology , population , political science , law
We investigated scientific publications on the prescription pattern of systemic hypertension drugs and use of guidelines in primary health care by systematic review and meta-analysis. Articles were selected in the PubMed, Web of Science and LILACS databases, according to the PRISMA statements, from 2004 to 2020. The systematic review showed a higher prescription pattern for combination therapy (52,9%). The meta-analysis confirmed the superiority of prescription for combination therapy (OR 1.76, CI 1.29 - 2.41). Was observed higher monotherapy prevalence in the Swedish study (98%) and combined therapy in Nigerian (98%). Higher frequency prescriptive of angiotensin-converting enzyme inhibitors in Trinidad (64%); diuretics (64%), beta blockers (63%), and calcium channel blockers (53%) in Nigeria; and angiotensin-receptor blockers (43%) in Portugal. Regarding the use of guidelines, 50% the studies reported their use for the prescription of antihypertensive in primary health care.