Open AccessAntifungal and antiaflatoxigenic activities of thymol and carvacrol against Aspergillus flavus
Author(s) -
Lydiana Pollis Nakasugi,
Natália Silva Bomfim,
Jéssica Cristina Zoratto Romoli,
Samuel Botião Nerilo,
Milena Veronezi Silva,
Gustavo Henrique Oliveira da Rocha,
Miguel Machinski
Publication year - 2021
Publication title -
saúde e pesquisa
Language(s) - English
Resource type - Journals
eISSN - 2176-9206
pISSN - 1983-1870
DOI - 10.17765/2176-9206.2021v14n1.e7727
Subject(s) - thymol , carvacrol , aspergillus flavus , aflatoxin , fungicide , mycotoxin , antifungal , chemistry , minimum inhibitory concentration , food science , biology , microbiology and biotechnology , botany , antibiotics , essential oil
The aim of this study was to evaluate the effects of thymol and carvacrol upon production of aflatoxins by Aspergillus flavus and upon its growth. Minimal inhibitory concentration (MIC), fungitoxic spectrum and mycotoxin inhibition were assessed. Results showed thymol and carvacrol exhibited fungicidal action, as determined by MIC values of 2500 and 30 µg mL-1, respectively. Both thymol and carvacrol significantly inhibited growth of A. flavus (p