Open AccessEVALUATION OF GLUTATHIONE REDUCTASE (GR) ACTIVITY IN LIVER OF FISH, CHANNA PUNCTATUS (BLOCH, 1793) EXPOSED TO HEXAVALENT CHROMIUM
Author(s) -
Yashika Awasthi and Sunil P. Trivedi
Publication year - 2019
Publication title -
journal of advanced zoology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.104
H-Index - 9
ISSN - 0253-7214
DOI - 10.17762/jaz.v40i01.30
Subject(s) - toxicant , hexavalent chromium , glutathione reductase , glutathione , toxicity , toxicology , antioxidant , biology , fish <actinopterygii> , chemistry , chromium , glutathione peroxidase , enzyme , biochemistry , fishery , organic chemistry
Antioxidant defence system is known to be a sensitive biomarker of metal exposure widely employed in predicting toxicity after sub-lethal exposure of Cr6+in fish. The present study conducted to assess the impact of Cr6+on Glutathione reductase (GR) activity in liver of fish, Channa punctatus. Fish were exposed to two different sub-lethal concentrations of Cr6+viz.,3.93 mg/L (5% of 96h LC50) (T1) and 7.85 mg/L (10% of 96h LC50) (T2) along with one control group without any toxicant exposure, for 15, 30 and 45 d. Results showa significant (p <0.05) increase in GR activity with an increase in dose and exposure period. This study emphasized the role of GR in monitoring of metal toxicity in aquatic regimes as an early warning tool.