Open AccessIdiopathic and symptomatic forms of genetic epilepsy
Author(s) -
А. Г. Малов
Publication year - 2022
Publication title -
èpilepsiâ i paroksizmalʹnye sostoâniâ
Language(s) - English
Resource type - Journals
eISSN - 2311-4088
pISSN - 2077-8333
DOI - 10.17749/2077-8333/epi.par.con.2022.107
Subject(s) - epilepsy , dravet syndrome , etiology , epilepsy syndromes , medicine , neuroscience , west syndrome , idiopathic generalized epilepsy , psychiatry , pediatrics , psychology
According to the new classification of the epilepsies proposed in 2017 by The International League Against Epilepsy, idiopathic epilepsies are recommended to refer to genetic epilepsy, suggesting to consider the term “idiopathic” as outdated. In connection with this, a tendency arose to refer forms of epilepsy previously called “idiopathic” as genetic epilepsy. However, idiopathic epilepsy constitutes just a part among genetic epilepsies. The other groups resulting from this etiology are monogenic epilepsies (e.g., Dravet syndrome) as well as symptomatic epilepsies due to other genetically determined syndromes (e.g., biotinidase deficiency or neuronal ceroid lipofuscinosis). The distinction between the three groups comprising genetic epilepsy is important not only due to difference in related etiology and course, but also because specific treatment in some monogenic forms might be possible. Here, the major criteria for distinguishing between such epilepsy groups are presented.