Open AccessTreatment of patients with prolonged course of medial temporal epilepsy
Author(s) -
В. Е. Китаева,
А. С. Котов
Publication year - 2018
Publication title -
èpilepsiâ i paroksizmalʹnye sostoâniâ
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.112
H-Index - 1
eISSN - 2311-4088
pISSN - 2077-8333
DOI - 10.17749/2077-8333.2018.10.3.031-037
Subject(s) - epilepsy , pharmacotherapy , medicine , drug resistant epilepsy , temporal lobe , pediatrics , anesthesia , psychiatry
Objective. The aim of the study was to evaluate the efficacy of treatment in patients with prolonged duration of medial temporal epilepsy (MTE). Materials and methods . We studied cases of 93 patients with history of MTE lasted more than 10 years. Results. This form of epilepsy is often characterized by drug resistance; therefore, patients have to try different medications before the effective one is found (in 12% of cases, patients tried 5-7 different medicines). Nevertheless, in 48.4% of patients, pharmacotherapy is ineffective. According to our findings, patients with an early MTE debut and those with an epileptogenic focus (by EEG / MRI data) in the medial temporal zone are most likely to have treatment-resistant epilepsy. Conclusion. If the therapy is ineffective, patients should be referred to preoperational examination.